Biosynthesis of uric acid labeled with radioactive carbon.

نویسندگان

  • J L KARLSSON
  • H A BARKER
چکیده

Sonne, Buchanan, and Delluva (1,2) have recently identified some of the precursors of the carbon atoms of uric acid in the pigeon. We have had occasion to repeat and extend their experiments during an investigation of the suitability of the pigeon as an agent for the biosynthesis of uric acid labeled in various positions with C14. This paper presents data on the yields of several different kinds of labeled uric acid obtained after injecting suitably labeled precursors and also provides information on the r6le of the methylene carbon of glycine’ in the synthesis of uric acid.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Simultaneous Voltammetric Measurement of Ascorbic Acid, Epinephrine, Uric Acid and Tyrosine at a Glassy Carbon Electrode Modified with Nanozeolite-Multiwall Carbon Nanotube

In this study, incorporation of iron ion-doped natrolite nanozeolite, multi-wall carbon nanotubes into chitosan-coated glassy carbon electrode for the simultaneous determination of ascorbic acid, epinephrine, uric acid and tyrosine is studied. The results show that the combination of multi-wall carbon nanotubes and iron ion-doped natrolite zeolite causes a dramatic enhancement in the sensitivit...

متن کامل

Simultaneous determination of dopamine and uric acid using a glassy carbon paste electrode modified with copper- para red complex

A simple approach based on cyclic voltammetry (CV) was developed for the simultaneous determination of dopamine (DA) and uric acid (UA) in the presence of ascorbic acid (AA) using a modified glassy carbon paste electrode (GCPE). In the present study, analytical parameters were optimized and electrochemical performance of modified electrode was investigated. The calibration curves were obtained ...

متن کامل

An efficient platform based on cupper complex-multiwalled carbon nanotube nanocomposite modified electrode for the determination of uric acid

A new voltammetric sensor for determination of uric acid (UA) by Cuppercomplex- multiwalled carbon nanotube (Cu-complex-CNT) nanocomposite modifiedcarbon paste electrode (CPE) is reported. The electrocatalytic behavior of theCu-complex-CNT nanocomposite modified CPE was studied in pH 2.0 phosphatebuffer solution by chronoamperometry (CA) and cyclic voltammetry (CV) in th...

متن کامل

Fabrication of Nano Poly Cresol Red over Glassy Carbon Electrode and its Application in Selective Determination of Uric acid in the Presence of Ascorbic Acid

A selective electrochemical method for the determination of uric acid was developed by using nano poly cresol red modified glassy carbon electrode. This new material has been characterized by Scanning Electron Microscopy, cyclic voltammetry and Differential pulse voltammetry. This modified electrode shows excellent electrocatalytic activity towards the oxidation of uric acid in the presence of ...

متن کامل

Nile Blue- Chitosan Composite as a new Electrochemical Sensor for Uric Acid on Glassy Carbon Electrode

Nile blue-Chitosan NB-CH as a new type of organic days-organic composite was made using Nile blue and chitosan. The NB-CH composite was made using a 0.005 M solution of Nile blue NB and a 7 solution of chitosan. To do this, a mixture of Nile blue and Chitosan with the ratio of 2:1 was prepared. The electrocatalytic oxidation of uric acid UA has been studied on glassy carbon electrode by NB-CH u...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Journal of biological chemistry

دوره 177 2  شماره 

صفحات  -

تاریخ انتشار 1949